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Answer:
A Study in Scarlet
it was published in Beeton's Christmas Annual in 1887
Answer:
His first Sherlock Holmes story, “A Study in Scarlet,” was published in Beeton's Christmas Annual in 1887. Starting in 1891, a series of Holmes stories appeared in The Strand magazine, and Conan Doyle was able to give up his medical practice and devote himself to writing.
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