Explain why protein degradation by proteasomes requires atp even though proteolysis is an exergonic process.

Question

24-03-2018
Biology

contestada

Explain why protein degradation by proteasomes requires atp even though proteolysis is an exergonic process.

Respuesta :

Otras preguntas

Grace invested $5,200 in an account paying an interest rate of 4.6% compounded daily. Assuming no deposits or withdrawals are made, how much money, to the neare

Use the information in the square to answer the questions about copper.

Given the function f(x) = 2|x + 6|- 4, for what values of x is f(x) = 6? x=-1, x = 11 x=-1, x=-11 x = 14, x=-26 x = 26. x=-14

You are interested in connecting with people of different backgrounds online. However, you don’t want a lot of stress or confusion, nor do you want anyone to fe

A horse runs for 15 seconds to the south at a speed of 12 m/s. What is thedisplacement of the horse in this time?A. 180 m southB. 150 m southC. 150 mD. 180 m

How might Athena feel about Arachne saying she is better than her at weaving and spinning?

What is the solution? X/12+3< or = 7

Please answer this correctly

jamuuj jamuuj · Answer 1 · 2018-04-07T08:12:41+02:00

Protasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Proteins are tagged for degradation with a small protein called ubiquitin, and the tagging reaction is catalyzed by enzymes called ubiquitin ligases. ATP is required to activate ubiquitin in the first step of linking it to the target protein.
The reaction is
Ubiquitin + E1.SH + ATP = Ub.S.E1 + AMP + PP